HER2 Positive Breast Cancer: Do You Know Your Status?

her2 herceptin Feb 19, 2020

Have you been told you have HER2 positive breast cancer? Most breast cancer patients know three things about their cancer:  stage, ER/PR status, and HER2 status. You know these things because they are the factors that determine what treatment you get. The stage tells us how aggressive to be with treatment. The hormone receptor status (ER/PR) tells us whether or not you need hormone blockers. The HER2 status tells us whether or not you need a therapy that is targeted at the HER2 receptor which is usually Herceptin®, also known as trastuzumab. About 15% to 20% of all invasive breast cancers are HER2 positive. 


What is HER2?


Just what is HER2? HER2 is an oncogene, and oncogenes often make proteins that promote the development of cancer or make cancers more aggressive.  The HER2 oncogene makes the HER2 protein. This protein is a receptor that sits on the surface of normal breast cells. Signals that are sent through this receptor are important for normal...

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